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MSX1

Gene
Official SymbolMSX1
Official Namemsh homeobox 1
BirdBase IDBB-GG14683
CGNC ID11159
also known asCHOX-7, GHOX-7, HOX-7, homeobox protein MSX-1|Hbox 7|homeobox protein GHOX-7|homeobox protein Hox-7|msh homeo box homolog 1|msh homeobox 1-like protein|msh homeobox homolog 1, Homeobox protein GHOX-7, Hox-7, CHOX-7 , Msx1
gene typeprotein-coding
Genomic Map
Ensembl
NCBI
UCSC
Gallus-Browse
Sequence Information
GenomicGenbank
RNANM_205488
PolypeptideNP_990819
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
UnigeneGga.1905
Microarray
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Zebrafish30527ENSDARG00000007641ZDB-GENE-980526-312ZFIN:ZDB-GENE-980526-312
Xenopus394692, 100125666, 399464490377
Mouse17701ENSMUSG00000048450All phenotypic alleles (6):Targeted, knock-out(2) Targeted, other(4) MGI:97168
Human4487ENSG00000163132MIM:608874MIM:142983
Gene Ontology
Molecular Functionp53 binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity
Biological Processactivation of meiosis, anterior/posterior pattern specification, apoptotic nuclear changes, BMP signaling pathway, BMP signaling pathway involved in heart development, bone morphogenesis, cartilage morphogenesis, embryonic forelimb morphogenesis, embryonic hindlimb morphogenesis, embryonic nail plate morphogenesis, epithelial to mesenchymal transition involved in endocardial cushion formation, face morphogenesis, forebrain development, in utero embryonic development, mammary gland epithelium development, mesenchymal cell proliferation, midbrain development, middle ear morphogenesis, multicellular organismal development, muscle organ development, negative regulation of apoptotic process, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of striated muscle cell differentiation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription regulatory region DNA binding, odontogenesis of dentin-containing tooth, palate development, positive regulation of BMP signaling pathway, positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator, positive regulation of mesenchymal cell apoptotic process, protein localization to nucleus, protein stabilization, regulation of odontogenesis, signal transduction involved in regulation of gene expression
Cellular Componentnucleus, transcription factor complex
Literature
Links to other databases
Entrez Gene396484
Ensembl GeneENSGALG00000015013
KEGGgga:396484