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MSX2

Gene
Official SymbolMSX2
Official Namemsh homeobox 2
BirdBase IDBB-GG14684
CGNC ID2130
also known asHOX-8, Msx-2, homeobox protein MSX-2|CHOX-8|GHox-8|homeobox protein Hox-8|homeobox-containing Hox-8|msh homeo box homolog 2|msh homeobox homolog 2, Homeobox protein MSX-2 , GHox-8, CHOX-8
gene typeprotein-coding
Genomic Map
Ensembl ID not known
NCBI
UCSC
Gallus-Browse
Sequence Information
GenomicGenbank
RNANM_204559
PolypeptideNP_989890
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
UnigeneGga.4977
Microarray
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Zebrafish30531, 573620ENSDARG00000056697ZDB-GENE-980526-492, ZDB-GENE-980526-322ZFIN:ZDB-GENE-980526-492, ZFIN:ZDB-GENE-980526-322
Xenopus394987, 373769852973
Mouse17702All phenotypic alleles (5):Targeted, knock-out(2) Targeted, other(3) MGI:97169
Human4488ENSG00000120149MIM:604757MIM:123101
Gene Ontology
Molecular Functionsequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription cofactor activity, transcription factor binding, transcription regulatory region DNA binding
Biological Processactivation of meiosis, anagen, anterior/posterior pattern specification, BMP signaling pathway involved in heart development, bone trabecula formation, branching involved in mammary gland duct morphogenesis, cellular response to estradiol stimulus, cellular response to growth factor stimulus, chondrocyte development, embryonic forelimb morphogenesis, embryonic hindlimb morphogenesis, embryonic nail plate morphogenesis, enamel mineralization, endochondral bone growth, epithelial to mesenchymal transition involved in endocardial cushion formation, frontal suture morphogenesis, negative regulation of apoptotic process, negative regulation of cell proliferation, negative regulation of CREB transcription factor activity, negative regulation of fat cell differentiation, negative regulation of keratinocyte differentiation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription regulatory region DNA binding, osteoblast development, outflow tract septum morphogenesis, positive regulation of BMP signaling pathway, positive regulation of catagen, positive regulation of mesenchymal cell apoptotic process, positive regulation of osteoblast differentiation, signal transduction involved in regulation of gene expression, transcription, DNA-templated, wound healing, spreading of epidermal cells
Cellular Componentcytoplasm, nucleus, transcription factor complex
Literature
Links to other databases
Entrez Gene395245
Ensembl Gene
KEGGgga:395245