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SMAD6

Gene
Official SymbolSMAD6
Official NameSMAD family member 6
BirdBase IDBB-GG17800
CGNC ID5950
also known asMADH6, mothers against decapentaplegic homolog 6|MAD homolog 6|mothers against DPP homolog 6
gene typeprotein-coding
Genomic Map
Ensembl ID not known
NCBI
UCSC
Gallus-Browse
Sequence Information
GenomicGenbank
RNANM_204248
PolypeptideNP_989579
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
UnigeneGga.3878
Microarray
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Zebrafish564395, 116992, 654727ENSDARG00000031763, ENSDARG00000053209ZDB-GENE-011015-1, ZDB-GENE-050419-198ZFIN:ZDB-GENE-011015-1, ZFIN:ZDB-GENE-050419-198
Xenopus100492635876705
Mouse17130ENSMUSG00000036867All phenotypic alleles (1):Targeted, other(1) MGI:1336883
Human4091MIM:602931
Gene Ontology
Molecular Functionchromatin binding, co-SMAD binding, I-SMAD binding, metal ion binding, R-SMAD binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding, transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity, type I activin receptor binding, type I transforming growth factor beta receptor binding, ubiquitin protein ligase binding
Biological Processcell-substrate adhesion, immune response, negative regulation of apoptotic process, negative regulation of BMP signaling pathway, negative regulation of cell proliferation, negative regulation of pathway-restricted SMAD protein phosphorylation, negative regulation of SMAD protein complex assembly, negative regulation of transforming growth factor beta receptor signaling pathway, response to laminar fluid shear stress, transcription, DNA-templated, transforming growth factor beta receptor signaling pathway, ureteric bud development, zygotic specification of dorsal/ventral axis
Cellular Componentnucleus, transcription factor complex
Literature
Links to other databases
Entrez Gene374096
Ensembl Gene
KEGGgga:374096