eGIFT
Genomes
Genes
Gene Expression-GEISHA
Microarray Expression Analysis
Pathways
Annotation--AgBase
Wiki
BirdBase Proposal Abstract
10,000 Genomes Project
SMAD6
Gene
Official Symbol
SMAD6
Official Name
SMAD family member 6
BirdBase ID
BB-GG17800
CGNC ID
5950
also known as
MADH6, mothers against decapentaplegic homolog 6|MAD homolog 6|mothers against DPP homolog 6
gene type
protein-coding
Genomic Map
Ensembl ID not known
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
Genbank
RNA
NM_204248
Polypeptide
NP_989579
Sequence Clusters/ESTs
Unigene
Gene Expression
In Situ Hybridization
GEISHA
Unigene
Gga.3878
Microarray
Orthology
Entrez Gene
Ensembl Gene
Genetic Phenotypes
MOD
Zebrafish
564395
,
116992
,
654727
ENSDARG00000031763
,
ENSDARG00000053209
ZDB-GENE-011015-1
,
ZDB-GENE-050419-198
ZFIN:ZDB-GENE-011015-1
,
ZFIN:ZDB-GENE-050419-198
Xenopus
100492635
876705
Mouse
17130
ENSMUSG00000036867
All phenotypic alleles (
1
):Targeted, other(
1
)
MGI:1336883
Human
4091
MIM:602931
Gene Ontology
Molecular Function
chromatin binding
,
co-SMAD binding
,
I-SMAD binding
,
metal ion binding
,
R-SMAD binding
,
sequence-specific DNA binding transcription factor activity
,
transcription regulatory region DNA binding
,
transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity
,
type I activin receptor binding
,
type I transforming growth factor beta receptor binding
,
ubiquitin protein ligase binding
Biological Process
cell-substrate adhesion
,
immune response
,
negative regulation of apoptotic process
,
negative regulation of BMP signaling pathway
,
negative regulation of cell proliferation
,
negative regulation of pathway-restricted SMAD protein phosphorylation
,
negative regulation of SMAD protein complex assembly
,
negative regulation of transforming growth factor beta receptor signaling pathway
,
response to laminar fluid shear stress
,
transcription, DNA-templated
,
transforming growth factor beta receptor signaling pathway
,
ureteric bud development
,
zygotic specification of dorsal/ventral axis
Cellular Component
nucleus
,
transcription factor complex
Literature
Links to other databases
Entrez Gene
374096
Ensembl Gene
KEGG
gga:374096