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SOX2

Gene
Official SymbolSOX2
Official NameSRY-box 2
BirdBase IDBB-GG17944
CGNC ID49650
also known astranscription factor SOX-2|SRY (sex determining region Y)-box 2|Sox2 transcription factor|cSox2|delta EF2a, Transcription factor SOX-2
gene typeprotein-coding
Genomic Map
Ensembl ID not known
NCBI
UCSC
Gallus-Browse
Sequence Information
GenomicGenbank
RNANM_205188
PolypeptideNP_990519
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
UnigeneGga.601
Microarray
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Zebrafish378723ENSDARG00000070913ZDB-GENE-030909-1ZFIN:ZDB-GENE-030909-1
Xenopus407873, 398000484552
Mouse20674ENSMUSG00000074637All phenotypic alleles (16):Radiation induced(1) Targeted, knock-out(4) Targeted, other(10) Transgenic(1) MGI:98364
Human6657ENSG00000181449MIM:206900MIM:184429
Gene Ontology
Molecular FunctionmiRNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding
Biological Processcell cycle arrest, endodermal cell fate specification, eye development, inner ear development, negative regulation of canonical Wnt signaling pathway, negative regulation of epithelial cell proliferation, negative regulation of neuron differentiation, osteoblast differentiation, pituitary gland development, positive regulation of MAPK cascade, positive regulation of transcription, DNA-templated, positive regulation of transcription from RNA polymerase II promoter, regulation of cysteine-type endopeptidase activity involved in apoptotic process, response to growth factor, response to wounding, somatic stem cell maintenance, transcription, DNA-templated
Cellular Componentcytosol, nucleus
Literature
Links to other databases
Entrez Gene396105
Ensembl Gene
KEGGgga:396105