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Official SymbolTGFB2
Official Nametransforming growth factor beta 2
BirdBase IDBB-GG18504
CGNC ID51471
also known asTGF-beta-2, transforming growth factor beta-2 proprotein|TGF beta2|transforming growth factor-beta2
gene typeprotein-coding
Genomic Map
Ensembl ID not known
Sequence Information
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Xenopus100489680, 373801480559
Mouse21808ENSMUSG00000039239All phenotypic alleles (4):Targeted, knock-out(2) Targeted, other(2) MGI:98726
Gene Ontology
Molecular Functionbeta-amyloid binding, growth factor activity, protein homodimerization activity, receptor binding, receptor signaling protein serine/threonine kinase activity, transforming growth factor beta receptor binding, type II transforming growth factor beta receptor binding
Biological Processactivation of protein kinase activity, cardiac epithelial to mesenchymal transition, cardiac muscle cell proliferation, cardioblast differentiation, cartilage development, cell-cell junction organization, cell cycle arrest, cell death, cell growth, cell migration, cell morphogenesis, collagen fibril organization, dopamine biosynthetic process, embryo development, embryo development ending in birth or egg hatching, embryonic digestive tract development, endothelial cell activation, epithelial to mesenchymal transition, epithelial to mesenchymal transition involved in endocardial cushion formation, extrinsic apoptotic signaling pathway, eye development, glial cell migration, gonad development, heart development, heart morphogenesis, hemopoiesis, lung development, negative regulation of alkaline phosphatase activity, negative regulation of cell adhesion, negative regulation of cell proliferation, negative regulation of epithelial cell proliferation, negative regulation of macrophage cytokine production, nervous system development, neural tube development, neuron development, neutrophil chemotaxis, organ development, pathway-restricted SMAD protein phosphorylation, positive regulation of cardioblast differentiation, positive regulation of catagen, positive regulation of cell adhesion mediated by integrin, positive regulation of cell cycle, positive regulation of cell division, positive regulation of cell growth, positive regulation of cell proliferation, positive regulation of epithelial cell migration, positive regulation of epithelial to mesenchymal transition, positive regulation of heart contraction, positive regulation of immune response, positive regulation of integrin biosynthetic process, positive regulation of neuron apoptotic process, positive regulation of phosphatidylinositol 3-kinase signaling, positive regulation of protein secretion, positive regulation of stress-activated MAPK cascade, protein phosphorylation, regulation of cell differentiation, regulation of cell proliferation, regulation of growth, regulation of transforming growth factor beta2 production, response to drug, response to hypoxia, response to progesterone, signal transduction by phosphorylation, skeletal muscle tissue development, SMAD protein import into nucleus, somatic stem cell division, somitogenesis, spleen development, transforming growth factor beta receptor signaling pathway, wound healing
Cellular Componentaxon, extracellular matrix, extracellular region, extracellular space, neuronal cell body
eGIFT Analysis
Links to other databases
Entrez Gene421352
Ensembl Gene