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Annotation--AgBase
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BirdBase Proposal Abstract
10,000 Genomes Project
CDC42
Gene
Official Symbol
CDC42
Official Name
cell division cycle 42
BirdBase ID
BB-GG1882
CGNC ID
3561
also known as
cell division control protein 42 homolog|G25K GTP-binding protein|cell division cycle 42 (GTP binding protein, 25kDa)
gene type
protein-coding
Genomic Map
Ensembl
NCBI
UCSC
Gallus-Browse
Sequence Information
Genomic
Genbank
RNA
NM_205048
Polypeptide
NP_990379
Sequence Clusters/ESTs
Unigene
Gene Expression
In Situ Hybridization
GEISHA
Unigene
Gga.4438
Microarray
Orthology
Entrez Gene
Ensembl Gene
Genetic Phenotypes
MOD
Zebrafish
793158
ZDB-GENE-030131-6069
ZFIN:ZDB-GENE-030131-6069
Xenopus
493389
,
379055
967584
Mouse
12540
ENSMUSG00000006699
All phenotypic alleles (
6
):Targeted, knock-out(
1
) Targeted, other(
4
) Gene trapped(
1
)
MGI:106211
Human
Gene Ontology
Molecular Function
apolipoprotein A-I receptor binding
,
GTPase activity
,
GTP binding
,
GTP-dependent protein binding
,
identical protein binding
,
protein kinase binding
,
thioesterase binding
Biological Process
actin cytoskeleton organization
,
actin filament bundle assembly
,
adherens junction organization
,
canonical Wnt signaling pathway
,
cardiac conduction system development
,
cellular protein localization
,
epithelial cell-cell adhesion
,
epithelial-mesenchymal cell signaling
,
establishment or maintenance of apical/basal cell polarity
,
filopodium assembly
,
GTP catabolic process
,
hair follicle morphogenesis
,
hair follicle placode formation
,
heart contraction
,
keratinization
,
keratinocyte development
,
maintenance of protein location
,
multicellular organism growth
,
negative regulation of gene expression
,
negative regulation of protein complex assembly
,
neuron fate determination
,
nuclear migration
,
positive regulation of cytokinesis
,
positive regulation of gene expression
,
positive regulation of hair follicle cell proliferation
,
positive regulation of MAPK cascade
,
positive regulation of peptidyl-serine phosphorylation
,
positive regulation of phosphatidylinositol 3-kinase activity
,
positive regulation of protein kinase activity
,
positive regulation of pseudopodium assembly
,
positive regulation of substrate adhesion-dependent cell spreading
,
regulation of attachment of spindle microtubules to kinetochore
,
regulation of filopodium assembly
,
regulation of mitosis
,
regulation of protein catabolic process
,
regulation of protein heterodimerization activity
,
regulation of protein stability
,
small GTPase mediated signal transduction
Cellular Component
adherens junction
,
apical part of cell
,
cell projection
,
cytoplasm
,
filopodium
,
midbody
,
mitotic spindle
,
neuronal cell body
,
neuron projection
,
plasma membrane
,
spindle midzone
Literature
eGIFT Analysis
Links to other databases
Entrez Gene
395917
Ensembl Gene
ENSGALG00000004796
KEGG
gga:395917