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VEGFA

Gene
Official SymbolVEGFA
Official Namevascular endothelial growth factor A
BirdBase IDBB-GG19421
CGNC ID7830
also known asVEGF, vascular endothelial growth factor A|VEGF-A|VPF|vascular permeability factor, Vascular endothelial growth factor A precursor , VEGF-A, Vascular permeability factor, VPF
gene typeprotein-coding
Genomic Map
Ensembl
NCBI
UCSC
Gallus-Browse
Sequence Information
GenomicGenbank
RNANM_001110355
PolypeptideNP_001103825
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
UnigeneGga.537
Microarray
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Zebrafish558154, 30682ENSDARG00000034700ZDB-GENE-030131-4605, ZDB-GENE-990415-273ZFIN:ZDB-GENE-030131-4605, ZFIN:ZDB-GENE-990415-273
Xenopus100038089, 100037058, 373589485743
Mouse22339ENSMUSG00000023951All phenotypic alleles (12):Targeted, knock-out(4) Targeted, other(8) MGI:103178
Human7422ENSG00000112715MIM:125853MIM:192240
Gene Ontology
Molecular Functionchemoattractant activity, fibronectin binding, growth factor activity, heparin binding, identical protein binding, platelet-derived growth factor receptor binding, protein heterodimerization activity, receptor agonist activity, vascular endothelial growth factor receptor 1 binding, vascular endothelial growth factor receptor 2 binding
Biological Processactivation of protein kinase activity, basophil chemotaxis, blood vessel maturation, cardiac vascular smooth muscle cell development, cell migration involved in sprouting angiogenesis, commissural neuron axon guidance, coronary artery morphogenesis, coronary vein morphogenesis, endothelial cell chemotaxis, epicardial cell to mesenchymal cell transition, lymph vessel morphogenesis, macrophage differentiation, monocyte differentiation, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of extrinsic apoptotic signaling pathway, negative regulation of neuron apoptotic process, negative regulation of transcription from RNA polymerase II promoter, outflow tract morphogenesis, positive regulation of angiogenesis, positive regulation of axon extension involved in axon guidance, positive regulation of branching involved in ureteric bud morphogenesis, positive regulation of cell division, positive regulation of cell migration involved in sprouting angiogenesis, positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway, positive regulation of CREB transcription factor activity, positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway, positive regulation of endothelial cell proliferation, positive regulation of ERK1 and ERK2 cascade, positive regulation of focal adhesion assembly, positive regulation of histone deacetylase activity, positive regulation of MAP kinase activity, positive regulation of mast cell chemotaxis, positive regulation of p38MAPK cascade, positive regulation of peptidyl-serine phosphorylation, positive regulation of peptidyl-tyrosine autophosphorylation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of positive chemotaxis, positive regulation of protein complex assembly, positive regulation of protein kinase B signaling, positive regulation of protein kinase C signaling, positive regulation of receptor internalization, positive regulation of retinal ganglion cell axon guidance, positive regulation of transcription from RNA polymerase II promoter in response to hypoxia, positive regulation of vascular endothelial growth factor receptor signaling pathway, positive regulation of vascular permeability, regulation of cell shape, tube formation
Cellular Componentcell surface, membrane, secretory granule
Literature
eGIFT Analysis
Links to other databases
Entrez Gene395909
Ensembl GeneENSGALG00000010290
KEGGgga:395909