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WNT4

Gene
Official SymbolWNT4
Official NameWnt family member 4
BirdBase IDBB-GG19605
CGNC ID3556
also known asprotein Wnt-4|Wnt-4 protein|wingless-type MMTV integration site family member 4, Wnt-4 protein precursor.
gene typeprotein-coding
Genomic Map
Ensembl
NCBI
UCSC
Gallus-Browse
Sequence Information
GenomicGenbank
RNANM_204783
PolypeptideNP_990114
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
UnigeneGga.305
Microarray
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Zebrafish30123, 791993ENSDARG00000071208, ENSDARG00000040159ZDB-GENE-980526-352, ZDB-GENE-000411-1ZFIN:ZDB-GENE-980526-352, ZFIN:ZDB-GENE-000411-1
Xenopus100491282, 397706484097
Mouse22417ENSMUSG00000036856All phenotypic alleles (11):Targeted, knock-out(4) Targeted, other(7) MGI:98957
Human54361ENSG00000162552MIM:158330MIM:603490
Gene Ontology
Molecular Functionfrizzled binding, transcription corepressor activity
Biological Processadrenal gland development, androgen biosynthetic process, branching involved in ureteric bud morphogenesis, canonical Wnt signaling pathway, cell fate commitment, cellular response to transforming growth factor beta stimulus, embryonic epithelial tube formation, epithelial to mesenchymal transition, establishment of protein localization to plasma membrane, female gonad development, female sex determination, immature T cell proliferation in thymus, kidney morphogenesis, liver development, male gonad development, mesenchymal to epithelial transition, mesonephric tubule development, metanephric nephron morphogenesis, negative regulation of apoptotic signaling pathway, negative regulation of canonical Wnt signaling pathway, negative regulation of cell differentiation, negative regulation of cell migration, negative regulation of fibroblast growth factor receptor signaling pathway, negative regulation of male gonad development, negative regulation of testicular blood vessel morphogenesis, negative regulation of testosterone biosynthetic process, negative regulation of transcription, DNA-templated, negative regulation of wound healing, neuron differentiation, non-canonical Wnt signaling pathway via MAPK cascade, oocyte development, paramesonephric duct development, positive regulation of aldosterone biosynthetic process, positive regulation of bone mineralization, positive regulation of canonical Wnt signaling pathway, positive regulation of collagen biosynthetic process, positive regulation of cortisol biosynthetic process, positive regulation of dermatome development, positive regulation of focal adhesion assembly, positive regulation of meiosis, positive regulation of osteoblast differentiation, positive regulation of Rho GTPase activity, positive regulation of stress fiber assembly, protein palmitoylation, regulation of cell-cell adhesion, renal vesicle formation, renal vesicle induction, smooth muscle cell differentiation, somatotropin secreting cell differentiation, tertiary branching involved in mammary gland duct morphogenesis, thyroid-stimulating hormone-secreting cell differentiation, Wnt signaling pathway
Cellular Componentcell surface, cytoplasm, extracellular space, proteinaceous extracellular matrix
Literature
Links to other databases
Entrez Gene395561
Ensembl GeneENSGALG00000004790
KEGGgga:395561