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GATA2

Gene
Official SymbolGATA2
Official NameGATA binding protein 2
BirdBase IDBB-GG3951
CGNC ID4415
also known asGATA-2, NF-E1b, GATA-binding factor 2|transcription factor NF-E1B, GATA-binding factor 2 , GATA-2, Transcription factor NF-E1B
gene typeprotein-coding
Genomic Map
Ensembl
NCBI
UCSC
Gallus-Browse
Sequence Information
GenomicGenbank
RNANM_001003797
PolypeptideNP_001003797
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
UnigeneGga.745
Microarray
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Zebrafish30480, 436962ENSDARG00000059327, ENSDARG00000009094ZDB-GENE-980526-260, ZDB-GENE-040718-440ZFIN:ZDB-GENE-980526-260, ZFIN:ZDB-GENE-040718-440
Xenopus100487142, 399273478164
Mouse14461ENSMUSG00000015053All phenotypic alleles (12):Targeted, knock-out(2) Targeted, other(10) MGI:95662
Human2624ENSG00000179348MIM:137295
Gene Ontology
Molecular FunctionC2H2 zinc finger domain binding, chromatin binding, protein binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II distal enhancer sequence-specific DNA binding, transcription factor binding, zinc ion binding
Biological Processcell differentiation in hindbrain, cell fate determination, cell maturation, central nervous system neuron development, definitive hemopoiesis, embryonic placenta development, eosinophil fate commitment, homeostasis of number of cells within a tissue, inner ear morphogenesis, negative regulation of fat cell differentiation, negative regulation of fat cell proliferation, negative regulation of macrophage differentiation, negative regulation of neural precursor cell proliferation, negative regulation of Notch signaling pathway, negative regulation of transcription from RNA polymerase II promoter, neuron fate commitment, pituitary gland development, positive regulation of angiogenesis, positive regulation of erythrocyte differentiation, positive regulation of megakaryocyte differentiation, regulation of histone acetylation, semicircular canal development, somatic stem cell maintenance, urogenital system development, ventral spinal cord interneuron differentiation
Cellular Componentnucleus, protein complex
Literature
eGIFT Analysis
Links to other databases
Entrez Gene416018
Ensembl GeneENSGALG00000005909
KEGGgga:416018