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GATA3

Gene
Official SymbolGATA3
Official NameGATA binding protein 3
BirdBase IDBB-GG3952
CGNC ID5080
also known ascGATA-3, GATA-binding factor 3|GATA-3|NF-E1|transcription factor NF-E1c, GATA-3, Transcription factor NF-E1C, GATA-binding factor 3
gene typeprotein-coding
Genomic Map
Ensembl ID not known
NCBI
UCSC
Gallus-Browse
Sequence Information
GenomicGenbank
RNANM_001008444
PolypeptideNP_001008444
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
UnigeneGga.744
Microarray
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Zebrafish30458ENSDARG00000016526ZDB-GENE-990415-82ZFIN:ZDB-GENE-990415-82
Xenopus448391, 399445485929
Mouse14462ENSMUSG00000015619All phenotypic alleles (12):Targeted, knock-out(5) Targeted, other(7) MGI:95663
Human2625ENSG00000107485MIM:146255MIM:131320
Gene Ontology
Molecular Functioncore promoter proximal region sequence-specific DNA binding, E-box binding, protein binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, transcription coactivator activity, transcription regulatory region DNA binding, zinc ion binding
Biological Processanatomical structure formation involved in morphogenesis, aortic valve morphogenesis, auditory receptor cell differentiation, axon guidance, canonical Wnt signaling pathway involved in metanephric kidney development, cardiac right ventricle morphogenesis, cell fate determination, ear development, kidney development, lymphocyte migration, male gonad development, mesenchymal to epithelial transition, mesonephros development, negative regulation of cell cycle, negative regulation of cell motility, negative regulation of cell proliferation, negative regulation of cell proliferation involved in mesonephros development, negative regulation of endothelial cell apoptotic process, negative regulation of fat cell differentiation, negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation, negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation, negative regulation of inflammatory response, negative regulation of transcription, DNA-templated, negative regulation of transcription from RNA polymerase II promoter, nephric duct formation, nephric duct morphogenesis, norepinephrine biosynthetic process, pharyngeal system development, phosphatidylinositol 3-kinase signaling, positive regulation of endothelial cell migration, positive regulation of interleukin-13 secretion, positive regulation of interleukin-4 production, positive regulation of interleukin-5 secretion, positive regulation of protein kinase B signaling, positive regulation of signal transduction, positive regulation of T cell differentiation, positive regulation of thyroid hormone generation, positive regulation of transcription, DNA-templated, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription regulatory region DNA binding, positive regulation of ureteric bud formation, regulation of cellular response to X-ray, regulation of cytokine biosynthetic process, regulation of nephron tubule epithelial cell differentiation, signal transduction, sympathetic nervous system development, T cell receptor signaling pathway, TOR signaling, ureteric bud formation, uterus development, ventricular septum development
Cellular Componentnuclear chromatin, nucleus
Literature
eGIFT Analysis
Links to other databases
Entrez Gene419106
Ensembl Gene
KEGGgga:419106