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IGF1

Gene
Official SymbolIGF1
Official Nameinsulin like growth factor 1
BirdBase IDBB-GG4795
CGNC ID9671
also known asIGF-1, IGF-I, insulin-like growth factor I|insulin-like growth factor 1 (somatomedin C)|somatomedin
gene typeprotein-coding
Genomic Map
Ensembl
NCBI
UCSC
Gallus-Browse
Sequence Information
GenomicGenbank
RNANM_001004384
PolypeptideNP_001004384
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
UnigeneGga.850
Microarray
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Zebrafish114433ENSDARG00000094132ZDB-GENE-010607-2ZFIN:ZDB-GENE-010607-2
Xenopus100486334, 378699480238
Mouse16000ENSMUSG00000020053All phenotypic alleles (12):Targeted, knock-out(7) Targeted, other(5) MGI:96432
Human3479ENSG00000017427MIM:608747MIM:147440
Gene Ontology
Molecular Functiongrowth factor activity, hormone activity, insulin-like growth factor receptor binding, insulin receptor binding, integrin binding
Biological Processbone mineralization involved in bone maturation, extrinsic apoptotic signaling pathway in absence of ligand, muscle hypertrophy, myoblast differentiation, myoblast proliferation, myotube cell development, negative regulation of apoptotic process, negative regulation of extrinsic apoptotic signaling pathway, negative regulation of release of cytochrome c from mitochondria, negative regulation of smooth muscle cell apoptotic process, phosphatidylinositol-mediated signaling, positive regulation of activated T cell proliferation, positive regulation of calcineurin-NFAT signaling cascade, positive regulation of cardiac muscle hypertrophy, positive regulation of DNA binding, positive regulation of epithelial cell proliferation, positive regulation of fibroblast proliferation, positive regulation of glucose import, positive regulation of glycogen biosynthetic process, positive regulation of glycolysis, positive regulation of insulin-like growth factor receptor signaling pathway, positive regulation of MAPK cascade, positive regulation of mitosis, positive regulation of osteoblast differentiation, positive regulation of phosphatidylinositol 3-kinase signaling, positive regulation of protein import into nucleus, translocation, positive regulation of Ras protein signal transduction, positive regulation of smooth muscle cell migration, positive regulation of smooth muscle cell proliferation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of tyrosine phosphorylation of Stat5 protein, proteoglycan biosynthetic process, regulation of multicellular organism growth, satellite cell maintenance involved in skeletal muscle regeneration
Cellular Componentextracellular space
Literature
eGIFT Analysis
Links to other databases
Entrez Gene418090
Ensembl GeneENSGALG00000012755
KEGGgga:418090