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HSPA5

Gene
Official SymbolHSPA5
Official Nameheat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
BirdBase IDBB-GG4708
CGNC ID667
also known asGRP78, endoplasmic reticulum chaperone BiP|78 kDa glucose-regulated protein|GRP-78|HSP70 family protein 5|biP|binding-immunoglobulin protein|heat shock 70 kDa protein 5|heat shock protein 70 family protein 5|heat shock protein family A member 5|immunoglobulin heavy chain-binding protein, 78 kDa glucose-regulated protein precursor (GRP 78), Immunoglobulin heavy chain binding protein
gene typeprotein-coding
Genomic Map
Ensembl
NCBI
UCSC
Gallus-Browse
Sequence Information
GenomicGenbank
RNANM_205491
PolypeptideNP_990822
Sequence Clusters/ESTsUnigene
Gene Expression
In Situ HybridizationGEISHA
UnigeneGga.4219
Microarray
Orthology
Entrez GeneEnsembl GeneGenetic PhenotypesMOD
Zebrafish378848ENSDARG00000004665ZDB-GENE-031001-11ZFIN:ZDB-GENE-031001-11
Xenopus100492570, 379756480059
Mouse14828ENSMUSG00000026864All phenotypic alleles (4):Targeted, knock-out(2) Targeted, other(2) MGI:95835
Human3309ENSG00000044574MIM:138120
Gene Ontology
Molecular FunctionATP binding, misfolded protein binding, protein binding, protein domain specific binding, ribosome binding, ubiquitin protein ligase binding
Biological Processactivation of signaling protein activity involved in unfolded protein response, cellular response to glucose starvation, cellular response to interleukin-4, cerebellar Purkinje cell layer development, cerebellum structural organization, ER overload response, negative regulation of apoptotic process, negative regulation of transforming growth factor beta receptor signaling pathway, positive regulation of protein ubiquitination, proteolysis involved in cellular protein catabolic process
Cellular Componentcell surface, COP9 signalosome, endoplasmic reticulum chaperone complex, endoplasmic reticulum-Golgi intermediate compartment, endoplasmic reticulum lumen, integral component of endoplasmic reticulum membrane, midbody
Literature
eGIFT Analysis
Links to other databases
Entrez Gene396487
Ensembl GeneENSGALG00000001000
KEGGgga:396487